A woman who received a pig kidney transplant — along with an implanted device to keep her heart beating — has died, her surgeon announced on Tuesday.

Lisa Pisano was near death from kidney and heart failure when surgeons at NYU Langone Health performed the dramatic pair of surgeries in April. The New Jersey woman initially seemed to be recovering well but about 47 days later, doctors had to remove the pig kidney and put Pisano back on dialysis after the organ was damaged by her heart medications.

Despite the dialysis and implanted heart pump, Pisano eventually entered hospice care and died on Sunday, NYU Langone transplant surgeon Dr Robert Montgomery said in a statement.

Montgomery praised Pisano’s bravery for attempting the latest pig organ-to-human experiment, what’s called xenotransplantation. The research aims to one day shore up the dire shortage of transplantable organs.

“Lisa helped bring us closer to realising a future where someone does not have to die for another person to live,” Montgomery said.

“She will forever be remembered for her courage and good nature.”

Back in April, the 54-year-old Pisano told AP that she knew the pig kidney might not work but “I just took a chance. And you know, worst case scenario, if it didn’t work for me, it might have worked for someone else”.

Pisano was the second patient ever to receive a kidney from a gene-edited pig. The first, Richard “Rick” Slayman, received his transplant at Massachusetts General Hospital and died in early May.