Parts of New York City descended into chaos for a fourth night on Sunday as largely peaceful demonstrations over the death of George Floyd turned into jarring scenes of flaming debris, human stampedes and looted storefronts.

As the night wore on violent confrontations erupted throughout Manhattan and Brooklyn. Protesters threw glass bottles and trash at the police, while large groups of officers charged down streets, pushing crowds of demonstrators aside and using batons as they made arrests.

In Lower Manhattan, some protesters shouted angrily at looters who were breaking into shops like a Duane Reade drugstore.

The city has been reeling from days of chaotic confrontations between protesters and the police that have resulted in dozens of injuries, hundreds of arrests, smashed windows and burned police vehicles.

On Sunday night thousands of demonstrators fanned across the city in different groups. One group crossed the Brooklyn Bridge and another briefly shut down the Manhattan Bridge.

Some groups paused every few blocks to take a knee, while others gathered in Times Square in Manhattan and outside the Barclays Center in Brooklyn.

A demonstration at Bryant Park in midtown Manhattan began with raised fists and a moment of silence. Many surrounding businesses had boarded up their windows in anticipation of trouble.

The protests in New York were part of escalating demonstrations in dozens of cities across the country that were sparked by a video capturing the final moments of Floyd, who was black, as a white police officer knelt on his neck for nearly nine minutes.

Some cities, including Los Angeles and Chicago, imposed curfews as the protests escalated, but officials in New York said that so far they would not order people off the streets.

After Saturday’s protests in New York, 33 police officers were injured, and 47 police vehicles were damaged or destroyed, the police said.

As of Sunday morning, about two dozen protesters had been transported to area hospitals for injuries, according to a spokesman for the New York Fire Department.

In SoHo, a series of small trash fires were set and stores were looted, including Bloomingdale’s and Chanel. One man with a gunshot wound was loaded into an ambulance.

The most jolting scenes of violence late on Sunday appeared to take place in Manhattan, where chaos erupted in Union Square at around 10pm. Flames nearly two stories high leapt from trash cans and piles of street debris in the neighborhood, sending acrid smoke into the air.

Protesters threw bottles and other objects at police officers armed with batons who pushed into crowds on Broadway and nearby side streets. As flames spread across one downtown street, officers ordered protesters to disperse.

“You are creating a disturbance,” an officer announced over as megaphone, as protesters shouted and sirens blared nearby. “You are being ordered to disperse. If you do not disperse, you will be subject to arrest.”

Nearby, looters smashed windows and stole merchandise from upscale stores. One group of young men took crowbars to the windows of a large clothing store but scattered when a loud banging noise announced the arrival of police officers at the end of the block.

“No protection for looters!” one protester could be heard shouting, as police officers sprinted towards a store.