An Israeli strike on a school where displaced people were sheltering in the central Gaza Strip killed at least 17 people on Thursday, nearly all women and children, Palestinian medical officials said.

The strike came as US Secretary of State Antony Blinken said Israel had accomplished its objective of “effectively dismantling” Hamas, and that negotiations over a cease-fire and the release of dozens of Israeli hostages would resume in the coming days.

Another 42 people were wounded in the strike in the built-up Nuseirat refugee camp, according to the Awda Hospital, which received the casualties. Among the dead were 13 children under the age of 18 and three women, according to the hospital's records.

The Israeli military said it targeted Hamas militants inside the school, without providing evidence. Israel has carried out several strikes on schools-turned-shelters in recent months, saying it precisely targets militants hiding out among civilians. The strikes often kill women and children.

Blinken, speaking to reporters in Qatar, which has served as a key mediator between Israel and Hamas, said negotiators would reconvene “in the coming days”.

“What we really have to determine is whether Hamas is prepared to engage," he said on his 11th visit to the region since the start of the war.

The United States hopes to renew the negotiations after Israeli forces killed top Hamas leader Yahya Sinwar in Gaza last week, but neither side has shown any sign of moderating its demands from months of negotiations that sputtered to a halt over the summer.

Blinken also announced an additional USD 135 million in US aid to the Palestinians, while again urging Israel to allow more assistance to enter the territory.

Health workers in besieged northern Gaza meanwhile warned of a catastrophic situation there, where Israel has been waging an air and ground offensive for more than two weeks.

Hospital director in northern Gaza says supplies are running out

Hundreds of people have been killed and tens of thousands have fled their homes in northern Gaza in recent days. The military says it is battling Hamas fighters who regrouped in the north, which was one of the first targets of the ground offensive at the start of the war.

Dr. Hossam Abu Safiyeh, the director of the Kamal Adwan Hospital in the north, said in a video message released Wednesday that some 150 wounded people were being treated there, including 14 children in intensive care or the neonatal department.

“There is a very large number of wounded people, and we lose at least one person every hour because of the lack of medical supplies and medical staff,” he said.

“Our ambulances can't transfer wounded people,” he said. “Those who can arrive by themselves to the hospital receive care, but those who don't just die in the streets.”

Footage shared with The Associated Press shows medical staff tending to premature babies and several older children in hospital beds, some with severe burns. One child is seen attached to a breathing machine, with bandages on her face and flies hovering over her.

“We are providing the bare minimum to patients. Everyone is paying the price of what is happening now in northern Gaza,” Abu Safiyeh said.

Kamal Adwan is one of three hospitals in the north left largely inaccessible because of the fighting. The war has gutted the health system across Gaza, with only 16 of 39 hospitals even partially functioning, according to the World Health Organisation.

First responders halt operations after saying Israel fired on them

The Civil Defence, first responders who operate under the Hamas-run government, said they had suspended operations in the north. They said Israeli forces fired on one of their teams in the town of Beit Lahiya after ordering them to relocate to the Indonesian Hospital, where troops are stationed.

Three Civil Defence members were wounded in the strike, and a firetruck was destroyed, it said. It said another five of its personnel were detained by Israeli forces at the hospital.

“As a result, we declare that Civil Defence operations in the northern Gaza Strip have been completely halted, leaving these areas without any firefighting, rescue, or emergency medical services,” it said in a statement.

There was no immediate comment from the Israeli military on the allegations.

The war began when Hamas-led militants stormed into southern Israel on October 7, 2023, killing some 1,200 people, mostly civilians, and abducting another 250. Around 100 hostages are still inside Gaza, a third of whom are believed to be dead.

Israel's retaliatory offensive has killed over 42,000 Palestinians, according to Gaza's Health Ministry, which does not say how many were combatants but says women and children make up more than half the fatalities. The Israeli military says it has killed over 17,000 fighters, without providing evidence.

The war has displaced around 90 per cent of Gaza's population of 2.3 million, often multiple times. Hundreds of thousands of people are crammed into tent camps along the coast after entire neighbourhoods in many areas were pounded to rubble.

Months of cease-fire negotiations brokered by the United States, Egypt and Qatar sputtered to a halt over the summer. The war has meanwhile expanded to Lebanon, where Israel launched a ground invasion more than three weeks ago after trading fire with the Hezbollah militant group for much of the past year.