A stoppage-time header from defender Simon Kjaer earned AC Milan a 1-1 draw at Manchester United in the blockbuster Europa League last-16 first-leg at Old Trafford on Thursday.

Kjaer’s goal after teenager Amad Diallo had given United the lead leaves the clash of the heavyweights in the balance ahead of the second leg in San Siro next week.

Arsenal are in a strong position thanks to a 3-1 win at Olympiacos in which Martin Odegaard scored his first goal for the club and Gabriel and Mohamed Elneny struck late on. The English side were knocked out last year by Olympiacos but now look set to progress, as do their north London rivals Tottenham Hotspur who had a Harry Kane brace to thank for a 2-0 home win over Croatian side Dinamo Zagreb.

Europa League regulars Villarreal and their La Liga rivals Granada are also well-placed to reach the last eight. Villarreal beat Dynamo Kyiv 2-0 away with goals by Pau Torres and Raul Albiol while Granada beat Molde 2-0 with former Tottenham striker Roberto Soldado on target.

Manchester United and Milan have clashed 10 times down the years in Europe, winning five apiece, but it was the first time they had locked horns since United claimed a 7-2 aggregate victory in the Champions League last 16 in 2010.

AS Roma beat Shakhtar Donetsk 3-0.